Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3
نویسندگان
چکیده
منابع مشابه
Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3
Distortion of primary cilium formation is increasingly recognized as a key event in many human pathologies. One of the underlying mechanisms involves aberrant activation of the lipogenic transcription factor sterol regulatory element-binding protein 1c (SREBP1c), as observed in cancer cells. To gain more insight into the molecular pathways by which SREBP1c suppresses primary ciliogenesis, we se...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2015
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e14-10-1472